Select Publications of Our Scientists

    physiological functions of the serotonin transporter. (2012) Biochem Pharmacol, 83(4):435-42. Epub
    2011 Oct 1. (Review)

    Zhong H, Haddjeri N, Sánchez C.  (2012) Escitalopram, an antidepressant with an allosteric effect at
    the serotonin transporter-a review of current understanding of its mechanism of action.
    Psychopharmacology (Berl). 219(1):1-13. Epub 2011 Sep 8. (Review)

    Hao, W., Chang, B.C., Tsao, C., Xu, J. (2010) Oligomycin-induced bioenergetic adaptation in cancer
    cells with heterogeneous bioenergetics organizations. J Biol Chem 285: 12647-12654

    Zhong H, Hansen KB, Boyle NJ, Han K, Muske G, Huang X, Egebjerg J, Sánchez C. (2009) An
    allosteric binding site at the human serotonin transporter mediates the inhibition of escitalopram by
    R-citalopram: kinetic binding studies with the ALI/VFL-SI/TT mutant. Neurosci Lett. 462(3):207-12.

    Walker MW, Wolinsky TD, Jubian V, Chandrasena G, Zhong H, Huang X, Miller S, Hegde LG,
    Marsteller DA, antagonist Lu AA33810  [N-[[trans-4-[(4,5-dihydro[1]benzothiepino[5,4- d]thiazol-2-
    yl)amino]cyclohexyl]methyl]-methanesulfonamide] exerts anxiolytic- and antidepressant-like effects
    in rat models of stress sensitivity. J Pharmacol Exp Ther. 328(3):900-11.

    Hao, W, Hu, Y.,Liu, C., Huang, X., Chang, B.C., Gibbons, J., Xu, J. (2008) Discovery of the catechol-
    containing compound as a Stat3 SH2 domain inhibitor by virtual screening. Bioorgan Med Chem
    Lett.  18: 4988-4992

    Xu, J., Ayyad, R., Chang, B.C., Asselin, M., Hao, W., Gibbons, J., Cole, D.C., Park, K. (2008) Inhibition
    of the Stat3 singaling pathway by 4-oxo-1-phenyl-1,4-dihydroquinoline-3-carboxylic acid ethyl
    esters. J Med Chem. 51: 4115-4121

    Titus SA, Li X, Southall N, Lu J, Inglese J, Brasch M, Austin CP, Zheng W. (2008) A Cell-based PDE4
    Assay in 1536-well plate format for High Throughput Screening. J Biomol Screen. 13(7):609-18.

    David DJ, Klemenhagen KC, Holick KA, Saxe MD, Mendez I, Santarelli L, Craig DA, Zhong H, Swanson
    CJ, Hegde LG, Ping XI, Dong D, Marzabadi MR, Gerald CP, Hen R. (2007) Efficacy of the MCHR1
    antagonist N-[3-(1-{[4-(3,4-difluorophenoxy)phenyl]methyl}(4-piperidyl))-4-methylphenyl]- 2-
    methylpropanamide (SNAP 94847) in mouse models of anxiety and depression following acute and
    chronic administration is independent of hippocampal neurogenesis. J Pharmacol Exp Ther. 321(1):

    Maloney, K.N., Hao, W., Xu, J., Gibbons, J., Hucul, J., Roll, D., Brady, S.F., Schroeder, F.C., Clardy, J.
    (2006) Phaeosphaeride A, a selective inhibitor of STAT3-dependent signaling isolated from an
    endophytic fungus. Org. Lett., 8: 4067 -4070

    Tang Y, Li X, He J, Lu J, Diwu Z. (2006) Real-time and high throughput monitoring of cAMP in live
    cells using a fluorescent membrane potential-sensitive dye. Assay Drug Dev Technol. 4(4):461-71.

    Swanson CJ, Blackburn TP, Zhang X, Zheng K, Xu ZQ, Hokfelt T, Wolinsky TD, Konkel MJ, Chen H,
    Zhong H, Walker MW, Craig DA, Gerald CP, Branchek TA. (2005) Anxiolytic- and antidepressant-like
    Sci U S A. 102(48):17489-94.

    Martin MB, Voeller HJ, Gelmann EP, Lu J, Stoica EG, Hebert EJ, Reiter R, Singh B, Danielsen M,
    Pentecost E, Stoica A. (2002) Role of cadmium in the regulation of AR gene expression and activity.
    Ung T.L., Cao C., Lu J., Ozato K., Dever T.E. (2001) Heterologous dimerization domains functionally
    substitute for the double-stranded RNA binding domains of the kinase PKR. EMBO J. 20(14):3728-37.

    Zhong H and Neubig RR. (2001) RGS Proteins: Novel Multifunctional Drug Targets.  J. Pharmcol. Exp.
    Ther. 297: 837-45. (Cover Review).
Zepicom scientists have published more than 30 articles in (peer-reviewed journals), most of which are listed
below with the link to resource on the website. Click the bluck link to see those most popular articles.
News & Publications
U-PHARM  Laboratories LLC
Accelerate drug discovery
Copyright © 2016. U-Pharm Laboratories LLC. All rights reserved.

239 New Road, Suite A-107
Parsippany, NJ 07054

Tel:   +1 (973) 789-8318
  +1 (973) 789-8188
Fax:  +1 (973) 287-7086
Follow Us